Inhaled corticosteroids (ICS) are commonly used in the treatment of chronic obstructive pulmonary disease (COPD). However, a new study reveals that ICS may not be as effective in treating the disease as previously thought. In a pooled study, researchers

Inhaled corticosteroids (ICS) are commonly used in the treatment of chronic obstructive pulmonary disease (COPD). However, a new study reveals that ICS may not be as effective in treating the disease as previously thought. In a pooled study, researchers from the University of Minnesota and Oregon Health and Science University, along with researchers from Canada, United Kingdom, and Europe analyzed data from nearly 4,000 patients with COPD, who were randomized and treated with either ICS or a placebo. Results showed that ICS use was associated with a significant FEV1 increase within the first 6 months of use and that they were more effective in improving lung function in ex-smokers than in current smokers. However, researchers found that after 6 months, there was no significant difference between placebo and ICS in modifying FEV1 decline. This study appears in the March issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians. ### News briefs from the journal Chest, March 2007 Contact: Jennifer Stawarz

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