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American cigarette manufacturers have filed a lawsuit against the FDA.
The largest US tobacco companies filed a lawsuit in the US District Court for the District of Columbia against the Federal Office of the Food and Drug Administration (FDA).
read more ...05/04/15
Interesting facts about cigarettes, countries - tobacco leaders.
Every minute in the world are sold about 8-10 million cigarettes and daily 13-15 billion cigarettes.
read more ...04/01/15
Anti-smoking campaigns run to extremes.
It is strange to what can bring the foolishness of anti-smoking crusaders in their attempts to impose all the rules of a healthy lifestyle, even if they lead to a violation of all norms, artistic freedom and civil society.
read more ...03/03/15
Smokers could be gene tested to find the most effective way to give up


A simple genetic test could help doctors tailor anti-smoking treatments to patients' needs, making it easier for them to quit.

The test allowed an Oxford University team to successfully predict which smokers would respond well to nicotine patches, and which wouldn't. The test is for common mutations in genes that control the metabolism of dopamine. Nicotine stimulates the production of dopamine in the nucleus accumbens, the brain's "pleasure centre". People with these mutations metabolise dopamine more quickly. They would therefore benefit from anti-smoking treatments that are designed to boost dopamine levels. But they are less likely to respond well to nicotine-replacement therapies, such as nicotine patches, says the team. John Stapleton of the National Addiction Centre in London finds the work interesting, but warns: "They are only looking at a few genes and there are potentially dozens involved. This is only part of the story." Tailored treatment The team found that a person's genotype affects not only whether they are likely to smoke or not, but how many cigarettes they consume. Between 30 and 40 per cent of people have mutations in genes that code for two enzymes involved in dopamine metabolism: dopamine-hydroxylase and monoamine oxidase. Heavy smokers are two to three times as likely to have mutations in these genes as non-smokers, says Robert Walton, one of the Oxford researchers. People with these mutations need to smoke more to maintain normal dopamine levels, so should be targeted with dopamine-boosting drugs such as buproprion, Walton says. Smokers without the mutations are more likely to be fast metabolisers of nicotine, and could be given nicotine patches. Nicotine replacement therapy is currently the most popular form of anti-smoking treatment, says Walton. "It's the most effective treatment, but the success rate is still only about 20 per cent. So if it doesn't work for you, you get pretty disheartened." In one study, the team found they could predict which of 800 smokers would respond to the patches. They are currently writing up these results for publication. Walton hopes the DNA test could be widely available in two to three years' time.

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