Association of smoking with urinary tract cancer quantified
WESTPORT, Aug 02 (Reuters Health) - Cigarette smokers are at a threefold higher risk of urinary tract cancer compared with nonsmokers, according to a report from Dutch researchers. In Europe, they say, half of urinary tract cancers in men and a third in w
Dr. Maurice P. A. Zeegers and colleagues from Maastricht University, Maastricht, The Netherlands, collected data from 43 epidemiologic studies. Through meta-regression analyses they calculated the odds ratios for different smoking characteristics and the incidence of urinary tract cancer.
They found that the risk of urinary tract cancer "increases with the number of cigarettes smoked per day and the number of years smoked." Their analysis also revealed that "both age at first exposure and cessation of cigarette smoking have an influence on modifying the risk of urinary tract cancer."
Dr. Zeegers' group calculated that the age- and gender-adjusted summary odds ratio for urinary tract cancer is 3.33 for current and former cigarette smokers and 1.98 for nonsmokers, according to their report in the August 1st issue of Cancer. These results, they say, were consistent across all the studies they analyzed, regardless of the differences in methodology between the studies.